General Information
SPKB ID SPKB06392
Signal sequence MPPSGLRLLLPLLLPLLWLLVLTPGRPAAGIL
Length 32
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..32
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06392.cif
Physicochemical Information
Molecular weight 3415.35704
Aliphatic index 185.9375
Isoelectric point 12.50010931
Charge (pH=7) 1.997977677
Topological polar surface area 1092.73
Aromaticity 0.03125
Average rotatable bonds 3.15625
Number of hydrogen bond donors 36
Number of hydrogen bond acceptors 38
X logP energy 0.07644
Hydropathy 
Literature Information
Title Pathogenic signal peptide variants in the human genome
Publication Year 2023
PubMed ID 37859801,
Patent ID NA,
