General Information
SPKB ID SPKB06391
Signal sequence MQMSPALTCLVLGLALVFGEGSAV
Length 24
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 1C5G,
Predicted Structure ID SPKB06391.cif
Physicochemical Information
Molecular weight 2407.92714
Aliphatic index 130
Isoelectric point 3.849962145
Charge (pH=7) -1.062215294
Topological polar surface area 864.91
Aromaticity 0.041666667
Average rotatable bonds 3.208333333
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 33
X logP energy -6.6183
Hydropathy 
Literature Information
Title Pathogenic signal peptide variants in the human genome
Publication Year 2023
PubMed ID 37859801,
Patent ID NA,
