General Information
SPKB ID SPKB06390
Signal sequence MAVESQGGRPLVLGLLLCVLGPVVSHAIG
Length 29
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..29
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06390.cif
Physicochemical Information
Molecular weight 2886.50714
Aliphatic index 151.0344828
Isoelectric point 7.360093818
Charge (pH=7) 0.028690486
Topological polar surface area 1071.97
Aromaticity 0
Average rotatable bonds 3.172413793
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 38
X logP energy -8.18853
Hydropathy 
Literature Information
Title Pathogenic signal peptide variants in the human genome
Publication Year 2023
PubMed ID 37859801,
Patent ID NA,
