General Information
SPKB ID SPKB06389
Signal sequence MIPAKDMAKVMIVMLAICFLTKSDGIK
Length 27
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..27
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06389.cif
Physicochemical Information
Molecular weight 2968.78454
Aliphatic index 119.2592593
Isoelectric point 9.514103177
Charge (pH=7) 1.935722416
Topological polar surface area 1030.27
Aromaticity 0.037037037
Average rotatable bonds 3.814814815
Number of hydrogen bond donors 36
Number of hydrogen bond acceptors 41
X logP energy -4.1876
Hydropathy 
Literature Information
Title Pathogenic signal peptide variants in the human genome
Publication Year 2023
PubMed ID 37859801,
Patent ID NA,
