General Information
SPKB ID SPKB06388
Signal sequence MRKHVLAASFSMRSLLVIMGDTDSIK
Length 26
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..26
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06388.cif
Physicochemical Information
Molecular weight 2907.50074
Aliphatic index 105
Isoelectric point 10.77379141
Charge (pH=7) 2.089189668
Topological polar surface area 1171.09
Aromaticity 0.038461538
Average rotatable bonds 3.884615385
Number of hydrogen bond donors 43
Number of hydrogen bond acceptors 42
X logP energy -10.71626
Hydropathy 
Literature Information
Title Pathogenic signal peptide variants in the human genome
Publication Year 2023
PubMed ID 37859801,
Patent ID NA,
