General Information
SPKB ID SPKB06387
Signal sequence MKQRFSALQLLKLLLLLQPPLPRAIL
Length 26
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..26
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06387.cif
Physicochemical Information
Molecular weight 3014.83904
Aliphatic index 172.6923077
Isoelectric point 12.53174703
Charge (pH=7) 3.997387609
Topological polar surface area 1089.79
Aromaticity 0.038461538
Average rotatable bonds 3.884615385
Number of hydrogen bond donors 36
Number of hydrogen bond acceptors 36
X logP energy -2.84706
Hydropathy 
Literature Information
Title Pathogenic signal peptide variants in the human genome
Publication Year 2023
PubMed ID 37859801,
Patent ID NA,
