General Information
SPKB ID SPKB06385
Signal sequence MWTLVSWVALTAGLVAGIT
Length 19
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06385.cif
Physicochemical Information
Molecular weight 1989.40334
Aliphatic index 143.6842105
Isoelectric point 6.099999998
Charge (pH=7) -0.002015701
Topological polar surface area 699.62
Aromaticity 0.105263158
Average rotatable bonds 3.105263158
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 25
X logP energy -3.0646
Hydropathy 
Literature Information
Title Pathogenic signal peptide variants in the human genome
Publication Year 2023
PubMed ID 37859801,
Patent ID NA,
