General Information
SPKB ID SPKB06384
Signal sequence MWGLKVLLLPVVSFAIL
Length 17
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06384.cif
Physicochemical Information
Molecular weight 1899.45154
Aliphatic index 194.7058824
Isoelectric point 9.700002532
Charge (pH=7) 0.997689266
Topological polar surface area 582.17
Aromaticity 0.117647059
Average rotatable bonds 3.470588235
Number of hydrogen bond donors 20
Number of hydrogen bond acceptors 21
X logP energy 2.3983
Hydropathy 
Literature Information
Title Pathogenic signal peptide variants in the human genome
Publication Year 2023
PubMed ID 37859801,
Patent ID NA,
