General Information
SPKB ID SPKB06383
Signal sequence MARKSNLPVLLVPFLLCQALVRCIS
Length 25
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06383.cif
Physicochemical Information
Molecular weight 2785.50664
Aliphatic index 152
Isoelectric point 9.914555929
Charge (pH=7) 2.873733211
Topological polar surface area 1020.6
Aromaticity 0.04
Average rotatable bonds 3.6
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 36
X logP energy -5.98716
Hydropathy 
Literature Information
Title Pathogenic signal peptide variants in the human genome
Publication Year 2023
PubMed ID 37859801,
Patent ID NA,
