SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06382

Signal sequence   MLLLLLLLGLR

Length  11

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..11



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06382.cif

Structure  SPKB06382.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1267.72244

Aliphatic index  283.6363636

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  416.22

Aromaticity  0

Average rotatable bonds  4

Number of hydrogen bond donors  15

Number of hydrogen bond acceptors  14

X logP energy  2.26287

Hydropathy 



Literature Information


Title  Distribution of Signal Peptides in Microvesicles from Activated Macrophage Cells

DOI  10.3390/ijms241512131,

Publication Year  2023

PubMed ID  37569508,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.