SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06375

Signal sequence   MATATLLAVLLLLLLVGSAGGA

Length  22

Organism  Artificial

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06375.cif

Structure  SPKB06375.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2068.58634

Aliphatic index  190.9090909

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  735.11

Aromaticity  0

Average rotatable bonds  3.045454545

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -4.2394

Hydropathy 



Literature Information


Title  Protein-Specific Signal Peptides for Mammalian Vector Engineering

DOI  10.1021/acssynbio.3c00157,

Publication Year  2023

PubMed ID  37487508,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.