General Information
SPKB ID SPKB06373
Signal sequence MPLLLLLPLLWAGALA
Length 16
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..16
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06373.cif
Physicochemical Information
Molecular weight 1705.21794
Aliphatic index 213.75
Isoelectric point 6.099999998
Charge (pH=7) -0.002015701
Topological polar surface area 498.03
Aromaticity 0.0625
Average rotatable bonds 3.125
Number of hydrogen bond donors 16
Number of hydrogen bond acceptors 18
X logP energy 3.2197
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
