General Information
SPKB ID SPKB06371
Signal sequence MKYLLPTAAAGLLLLAAQPAMA
Length 22
Organism Cricetulus cricetus
UniProt ID NA,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 1QOK,
Predicted Structure ID SPKB06371.cif
Physicochemical Information
Molecular weight 2228.77964
Aliphatic index 138.1818182
Isoelectric point 9.298300651
Charge (pH=7) 0.996838851
Topological polar surface area 766.41
Aromaticity 0.045454545
Average rotatable bonds 3.136363636
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 29
X logP energy -3.1314
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
