SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06361

Signal sequence   MWWRLWWLLLLLLLLWLALAAAA

Length  23

Organism  Cricetulus cricetus

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06361.cif

Structure  SPKB06361.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2836.60874

Aliphatic index  208.2608696

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  844.37

Aromaticity  0.217391304

Average rotatable bonds  3.652173913

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  26

X logP energy  8.30687

Hydropathy 



Literature Information


Title  Protein-Specific Signal Peptides for Mammalian Vector Engineering

DOI  10.1021/acssynbio.3c00157,

Publication Year  2023

PubMed ID  37487508,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.