General Information
SPKB ID SPKB06360
Signal sequence MKMGVRLAARAWPLCGLLLAALGGVCA
Length 27
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..27
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06360.cif
Physicochemical Information
Molecular weight 2742.45904
Aliphatic index 130.3703704
Isoelectric point 9.914555929
Charge (pH=7) 2.873733211
Topological polar surface area 976.74
Aromaticity 0.037037037
Average rotatable bonds 3.259259259
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 35
X logP energy -5.51176
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
