General Information
SPKB ID SPKB06359
Signal sequence MAATVRRQRPRRLLCWTLVAVLLADLLALS
Length 30
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..30
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06359.cif
Physicochemical Information
Molecular weight 3407.18874
Aliphatic index 149.6666667
Isoelectric point 12.32403132
Charge (pH=7) 3.936439511
Topological polar surface area 1364.8
Aromaticity 0.033333333
Average rotatable bonds 3.7
Number of hydrogen bond donors 52
Number of hydrogen bond acceptors 43
X logP energy -9.38265
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
