General Information
SPKB ID SPKB06358
Signal sequence MLRISGRNMKVLFAAALIVGSVVFLLLPGPSVA
Length 33
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..33
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06358.cif
Physicochemical Information
Molecular weight 3441.28364
Aliphatic index 150.6060606
Isoelectric point 12.51647815
Charge (pH=7) 2.997682643
Topological polar surface area 1230.54
Aromaticity 0.060606061
Average rotatable bonds 3.363636364
Number of hydrogen bond donors 43
Number of hydrogen bond acceptors 43
X logP energy -6.95366
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
