General Information
SPKB ID SPKB06357
Signal sequence MKILLLCVGLLLTWDNGMVLG
Length 21
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06357.cif
Physicochemical Information
Molecular weight 2302.92014
Aliphatic index 176.1904762
Isoelectric point 6.160569088
Charge (pH=7) -0.063838966
Topological polar surface area 787.75
Aromaticity 0.047619048
Average rotatable bonds 3.666666667
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 29
X logP energy -1.3108
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
