General Information
SPKB ID SPKB06356
Signal sequence MRSLLLASFCLLAVALA
Length 17
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06356.cif
Physicochemical Information
Molecular weight 1792.27134
Aliphatic index 178.2352941
Isoelectric point 8.549912035
Charge (pH=7) 0.936006272
Topological polar surface area 631.28
Aromaticity 0.058823529
Average rotatable bonds 3.411764706
Number of hydrogen bond donors 24
Number of hydrogen bond acceptors 23
X logP energy -2.65923
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
