General Information
SPKB ID SPKB06355
Signal sequence MKFPMVAAALLLLCAVRA
Length 18
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06355.cif
Physicochemical Information
Molecular weight 1918.49094
Aliphatic index 146.6666667
Isoelectric point 9.833242293
Charge (pH=7) 1.935711238
Topological polar surface area 637.15
Aromaticity 0.055555556
Average rotatable bonds 3.388888889
Number of hydrogen bond donors 23
Number of hydrogen bond acceptors 24
X logP energy -1.18703
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
