General Information
SPKB ID SPKB06354
Signal sequence MRVLWVLGLCCVLLTFGFVRA
Length 21
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06354.cif
Physicochemical Information
Molecular weight 2397.04194
Aliphatic index 152.8571429
Isoelectric point 8.834915637
Charge (pH=7) 1.874028245
Topological polar surface area 805.14
Aromaticity 0.142857143
Average rotatable bonds 3.571428571
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 28
X logP energy -1.03906
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
