General Information
SPKB ID SPKB06353
Signal sequence MRFSCLALLPGVALLLASARLAAA
Length 24
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06353.cif
Physicochemical Information
Molecular weight 2429.02324
Aliphatic index 155
Isoelectric point 10.52640717
Charge (pH=7) 1.936002961
Topological polar surface area 888.09
Aromaticity 0.041666667
Average rotatable bonds 3.208333333
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 31
X logP energy -5.75896
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
