General Information
SPKB ID SPKB06352
Signal sequence MLSRSLLCLALAWVARVGA
Length 19
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06352.cif
Physicochemical Information
Molecular weight 2030.52054
Aliphatic index 154.2105263
Isoelectric point 10.52640717
Charge (pH=7) 1.936002961
Topological polar surface area 767.17
Aromaticity 0.052631579
Average rotatable bonds 3.421052632
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 26
X logP energy -4.70376
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
