General Information
SPKB ID SPKB06351
Signal sequence MRWKIIQLQYCFLLVPCMLTALEA
Length 24
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06351.cif
Physicochemical Information
Molecular weight 2884.61014
Aliphatic index 134.1666667
Isoelectric point 8.221180783
Charge (pH=7) 0.874661231
Topological polar surface area 991.48
Aromaticity 0.125
Average rotatable bonds 3.875
Number of hydrogen bond donors 36
Number of hydrogen bond acceptors 36
X logP energy -1.47693
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
