General Information
SPKB ID SPKB06350
Signal sequence MASSGSVQQPRLVLLMLVLAGAARA
Length 25
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06350.cif
Physicochemical Information
Molecular weight 2540.08074
Aliphatic index 132.8
Isoelectric point 12.50010931
Charge (pH=7) 1.997977677
Topological polar surface area 1023.6
Aromaticity 0
Average rotatable bonds 3.36
Number of hydrogen bond donors 36
Number of hydrogen bond acceptors 35
X logP energy -10.35886
Hydropathy
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,