General Information
SPKB ID SPKB06349
Signal sequence MGKSPEAWCIVLFSVLASFSA
Length 21
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06349.cif
Physicochemical Information
Molecular weight 2243.66384
Aliphatic index 97.61904762
Isoelectric point 6.231833229
Charge (pH=7) -0.062510328
Topological polar surface area 796.56
Aromaticity 0.142857143
Average rotatable bonds 3.285714286
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 30
X logP energy -5.4028
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
