General Information
SPKB ID SPKB06348
Signal sequence MRYVASYLLAALGGNS
Length 16
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..16
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 2LBF,
Predicted Structure ID SPKB06348.cif
Physicochemical Information
Molecular weight 1685.95854
Aliphatic index 110
Isoelectric point 9.17162813
Charge (pH=7) 0.99628016
Topological polar surface area 685.73
Aromaticity 0.125
Average rotatable bonds 3.3125
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 24
X logP energy -6.43993
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
