General Information
SPKB ID SPKB06347
Signal sequence MQELRGILLCLLLAAAVPTTP
Length 21
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06347.cif
Physicochemical Information
Molecular weight 2223.76064
Aliphatic index 158.0952381
Isoelectric point 6.232433001
Charge (pH=7) -0.062218605
Topological polar surface area 810.49
Aromaticity 0
Average rotatable bonds 3.333333333
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 29
X logP energy -4.38543
Hydropathy
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,