General Information
SPKB ID SPKB06346
Signal sequence MLLSVPLLLGLLGLAAA
Length 17
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06346.cif
Physicochemical Information
Molecular weight 1665.15074
Aliphatic index 218.2352941
Isoelectric point 6.099999998
Charge (pH=7) -0.002015701
Topological polar surface area 540.36
Aromaticity 0
Average rotatable bonds 3.117647059
Number of hydrogen bond donors 18
Number of hydrogen bond acceptors 20
X logP energy -0.246
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
