General Information
SPKB ID SPKB06345
Signal sequence MLLGPGHTLSAPALALAVTLTLLVRSASP
Length 29
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..29
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06345.cif
Physicochemical Information
Molecular weight 2871.47464
Aliphatic index 144.8275862
Isoelectric point 10.5517587
Charge (pH=7) 1.088890079
Topological polar surface area 1063.71
Aromaticity 0
Average rotatable bonds 3
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 39
X logP energy -9.36413
Hydropathy
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,