General Information
SPKB ID SPKB06344
Signal sequence MAPFASLASGILLLLSLITSSKA
Length 23
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06344.cif
Physicochemical Information
Molecular weight 2304.81364
Aliphatic index 153.0434783
Isoelectric point 9.700002532
Charge (pH=7) 0.997689266
Topological polar surface area 842.13
Aromaticity 0.043478261
Average rotatable bonds 3.260869565
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 32
X logP energy -6.883
Hydropathy 
Literature Information
Title Protein-Specific Signal Peptides for Mammalian Vector Engineering
DOI 10.1021/acssynbio.3c00157,
Publication Year 2023
PubMed ID 37487508,
Patent ID NA,
