Peptide-Information

General Information

SPKB ID SPKB06339

Signal sequence MRVMAPRTLILLLSGALALTETWA

Length 24

Organism Homo sapiens (Human)

UniProt ID NA,

Motif 1..24

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB06339.cif

Structure SPKB06339.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2628.22984

Aliphatic index 142.5

Isoelectric point 10.39777148

Charge (pH=7) 0.9997528

Topological polar surface area 981.64

Aromaticity 0.041666667

Average rotatable bonds 3.5

Number of hydrogen bond donors 36

Number of hydrogen bond acceptors 34

X logP energy -5.49916

Hydropathy

Literature Information

Title HLA class I signal peptide polymorphism determines the level of CD94/NKG2-HLA-E-mediated regulation of effector cell responses

Publication Year 2023

PubMed ID 37264229,

Patent ID NA,