General Information
SPKB ID SPKB06336
Signal sequence MKTIIALSYIFCLVFA
Length 16
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..16
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06336.cif
Physicochemical Information
Molecular weight 1833.32044
Aliphatic index 152.5
Isoelectric point 8.522939048
Charge (pH=7) 0.934864135
Topological polar surface area 586.53
Aromaticity 0.1875
Average rotatable bonds 3.625
Number of hydrogen bond donors 22
Number of hydrogen bond acceptors 23
X logP energy 0.2153
Hydropathy 
Literature Information
Title Improved Split TEV GPCR beta-arrestin-2 Recruitment Assays via Systematic Analysis of Signal Peptide and beta-arrestin Binding Motif Variants
DOI 10.3390/bios13010048,
Publication Year 2022
PubMed ID 36671883,
Patent ID NA,
