SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06335

Signal sequence   MDECLLFLTTIDEDESLSTNAFA

Length  23

Organism  Bacillus subtilis DB104

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06335.cif

Structure  SPKB06335.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2578.84224

Aliphatic index  93.4782608695652

Isoelectric point  3.14100263803266

Charge (pH=7)   -6.05732559583017

Topological polar surface area  1071.56

Aromaticity  0.0869565217391304

Average rotatable bonds  3.69565217391304

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  38

X logP energy  -10.4765999999999

Hydropathy 



Literature Information


Title  Signal Peptide Efficiency: From High-Throughput Data to Prediction and Explanation

DOI  10.1021/acssynbio.2c00328,

Publication Year  2023

PubMed ID  36649479,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.