General Information
SPKB ID SPKB06317
Signal sequence MQLLRCFSIFSVIASVLA
Length 18
Organism Saccharomyces cerevisiae
UniProt ID P32781,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06317.cif
Physicochemical Information
Molecular weight 1998.47244
Aliphatic index 151.6666667
Isoelectric point 8.549912035
Charge (pH=7) 0.936006272
Topological polar surface area 723.7
Aromaticity 0.111111111
Average rotatable bonds 3.611111111
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 26
X logP energy -4.10383
Hydropathy 
Literature Information
Title Proteome-Scale Screening to Identify High-Expression Signal Peptides with Minimal N-Terminus Biases via Yeast Display
DOI 10.1021/acssynbio.2c00101,
Publication Year 2022
PubMed ID 35687717,
Patent ID NA,
