SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06306

Signal sequence   MRAKLLGIVLTTPIAISSFA

Length  20

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  4K07,

Predicted Structure ID  SPKB06306.cif

Structure  SPKB06306.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2102.60664

Aliphatic index  146.5

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  776.27

Aromaticity  0.05

Average rotatable bonds  3.4

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -5.12633

Hydropathy 



Literature Information


Title  Enhancing extracellular production of lipoxygenase in Escherichia coli by signal peptides and autolysis system

DOI  10.1186/s12934-022-01772-x,

Publication Year  2022

PubMed ID  35305645,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.