SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06304

Signal sequence   MSALTSQPTSSGSSEKIPRLRGWRAKAAGVVLAALALTTGVAAPAPAAA

Length  49

Organism  Amycolatopsis mediterranei

UniProt ID  NA,

Motif  1..49



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06304.cif

Structure  SPKB06304.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4761.52054

Aliphatic index  92.04081633

Isoelectric point  12.24365703

Charge (pH=7)   3.999159421

Topological polar surface area  1961.18

Aromaticity  0.020408163

Average rotatable bonds  3.040816327

Number of hydrogen bond donors  70

Number of hydrogen bond acceptors  68

X logP energy  -25.14539

Hydropathy 



Literature Information


Title  Extracellular secretion of a cutinase with polyester-degrading potential by E. coli using a novel signal peptide from Amycolatopsis mediterranei

DOI  10.1007/s11274-022-03246-z,

Publication Year  2022

PubMed ID  35195792,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.