General Information
SPKB ID SPKB06283
Signal sequence YGRKKRRQRRRASPLHRCIYAVRPTG
Length 26
Organism Herpes Simplex Virus Type 1 (HSV1)
UniProt ID NA,
Motif 1..26
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06283.cif
Physicochemical Information
Molecular weight 3182.75554
Aliphatic index 48.84615385
Isoelectric point 12.51003691
Charge (pH=7) 10.02460129
Topological polar surface area 1473.17
Aromaticity 0.076923077
Average rotatable bonds 4.076923077
Number of hydrogen bond donors 58
Number of hydrogen bond acceptors 44
X logP energy -16.62354
Hydropathy 
Literature Information
Title Blocking HSV-1 glycoprotein K binding to signal peptide peptidase reduces virus infectivity in vitro and in vivo
DOI 10.1371/journal.ppat.1009848,
Publication Year 2021
PubMed ID 34352042,
Patent ID NA,
