General Information
SPKB ID SPKB06281
Signal sequence RRVRSFLRGLPALLLLLLFLGPWPAAV
Length 27
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..27
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06281.cif
Physicochemical Information
Molecular weight 3045.79994
Aliphatic index 162.5925926
Isoelectric point 12.97714556
Charge (pH=7) 3.997971054
Topological polar surface area 1077.17
Aromaticity 0.111111111
Average rotatable bonds 3.444444444
Number of hydrogen bond donors 39
Number of hydrogen bond acceptors 33
X logP energy -2.17412
Hydropathy 
Literature Information
Title Cross-presentation of a TAP-independent signal peptide induces CD8 T immunity to escaped cancers but necessitates anchor replacement
DOI 10.1007/s00262-021-02984-7,
Publication Year 2022
PubMed ID 34142235,
Patent ID NA,
