Peptide-Information

General Information

SPKB ID SPKB06280

Signal sequence RSFLRGLPALLLLLLFLGPWPAAV

Length 24

Organism Homo sapiens (Human)

UniProt ID NA,

Motif 1..24

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB06280.cif

Structure SPKB06280.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2634.29234

Aliphatic index 170.8333333

Isoelectric point 12.50010931

Charge (pH=7) 1.997977677

Topological polar surface area 866.07

Aromaticity 0.125

Average rotatable bonds 3.25

Number of hydrogen bond donors 30

Number of hydrogen bond acceptors 28

X logP energy 0.18894

Hydropathy

Literature Information

Title Cross-presentation of a TAP-independent signal peptide induces CD8 T immunity to escaped cancers but necessitates anchor replacement

Publication Year 2022

PubMed ID 34142235,

Patent ID NA,