General Information
SPKB ID SPKB06279
Signal sequence RGLPALLLLLFLGPWPAAV
Length 19
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06279.cif
Physicochemical Information
Molecular weight 2017.53124
Aliphatic index 174.7368421
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 638.44
Aromaticity 0.105263158
Average rotatable bonds 3
Number of hydrogen bond donors 21
Number of hydrogen bond acceptors 21
X logP energy 1.17447
Hydropathy
Literature Information
Title Cross-presentation of a TAP-independent signal peptide induces CD8 T immunity to escaped cancers but necessitates anchor replacement
DOI 10.1007/s00262-021-02984-7,
Publication Year 2022
PubMed ID 34142235,
Patent ID NA,