General Information
SPKB ID SPKB06278
Signal sequence FLGPWPAAV
Length 9
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..9
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06278.cif
Physicochemical Information
Molecular weight 957.13994
Aliphatic index 97.77777778
Isoelectric point 6.099999998
Charge (pH=7) -0.002015701
Topological polar surface area 294.33
Aromaticity 0.222222222
Average rotatable bonds 2.444444444
Number of hydrogen bond donors 9
Number of hydrogen bond acceptors 10
X logP energy 0.6291
Hydropathy
Literature Information
Title Cross-presentation of a TAP-independent signal peptide induces CD8 T immunity to escaped cancers but necessitates anchor replacement
DOI 10.1007/s00262-021-02984-7,
Publication Year 2022
PubMed ID 34142235,
Patent ID NA,