Peptide-Information

General Information

SPKB ID SPKB06276

Signal sequence MAFLWLLSCWALLGTTFG

Length 18

Organism Homo sapiens (Human)

UniProt ID NA,

Motif 1..18

Activity Information

Pathway SRP-dependent

Natural/Artificial Artificial

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB06276.cif

Structure SPKB06276.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2030.47304

Aliphatic index 119.4444444

Isoelectric point 5.922539791

Charge (pH=7) -0.063990417

Topological polar surface area 650.29

Aromaticity 0.222222222

Average rotatable bonds 3.333333333

Number of hydrogen bond donors 25

Number of hydrogen bond acceptors 24

X logP energy -0.4568

Hydropathy

Literature Information

Title Evaluation of artificial signal peptides for secretion of two lysosomal enzymes in CHO cells

Publication Year 2021

PubMed ID 34032266,

Patent ID NA,