Peptide-Information

General Information

SPKB ID SPKB06275

Signal sequence METDTLLLWVLLLWVPGSTGD

Length 21

Organism Mus musculus (Mouse)

UniProt ID NA,

Motif 1..21

Activity Information

Pathway SRP-dependent

Natural/Artificial Artificial

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID 4KUC,

Predicted Structure ID SPKB06275.cif

Structure SPKB06275.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2359.76254

Aliphatic index 139.047619

Isoelectric point 3.380030198

Charge (pH=7) -2.99934761

Topological polar surface area 860.93

Aromaticity 0.095238095

Average rotatable bonds 3.428571429

Number of hydrogen bond donors 30

Number of hydrogen bond acceptors 30

X logP energy -3.3981

Hydropathy

Literature Information

Title Evaluation of artificial signal peptides for secretion of two lysosomal enzymes in CHO cells

Publication Year 2021

PubMed ID 34032266,

Patent ID NA,