SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06271

Signal sequence   MKLERLLAMVVLLISKKQVQA

Length  21

Organism  Bacillus subtilis

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06271.cif

Structure  SPKB06271.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2412.07714

Aliphatic index  162.3809524

Isoelectric point  11.07952226

Charge (pH=7)   2.998871009

Topological polar surface area  928.99

Aromaticity  0

Average rotatable bonds  4.19047619

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  32

X logP energy  -4.07673

Hydropathy 



Literature Information


Title  Optimal secretion of thermostable Beta-glucosidase in Bacillus subtilis by signal peptide optimization

DOI  10.1016/j.pep.2021.105843,

Publication Year  2021

PubMed ID  33631310,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.