General Information
SPKB ID SPKB06262
Signal sequence MKWVTFISLLFLFSAYS
Length 17
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06262.cif
Physicochemical Information
Molecular weight 2053.48964
Aliphatic index 114.7058824
Isoelectric point 9.298300651
Charge (pH=7) 0.996838851
Topological polar surface area 671.88
Aromaticity 0.294117647
Average rotatable bonds 3.705882353
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 25
X logP energy -0.3444
Hydropathy
Literature Information
Title Comparison of Different Signal Peptides for the Efficient Secretion of the Sweet-Tasting Plant Protein Brazzein in Pichia pastoris
DOI 10.3390/life11010046,
Publication Year 2021
PubMed ID 33450886,
Patent ID NA,