General Information
SPKB ID SPKB06257
Signal sequence MRFPSIFTAVLFAASSALAAPVNTTTEDETAQIPAEAVIGYSDLEGDFDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLEKR
Length 85
Organism Saccharomyces cerevisiae
UniProt ID NA,
Motif 1..85
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6KRL,
Predicted Structure ID SPKB06257.cif
Physicochemical Information
Molecular weight 8939.01224
Aliphatic index 95.41176471
Isoelectric point 3.84316662
Charge (pH=7) -6.989251009
Topological polar surface area 3661.15
Aromaticity 0.082352941
Average rotatable bonds 3.388235294
Number of hydrogen bond donors 124
Number of hydrogen bond acceptors 125
X logP energy -40.01226
Hydropathy
Literature Information
Title Comparison of Different Signal Peptides for the Efficient Secretion of the Sweet-Tasting Plant Protein Brazzein in Pichia pastoris
DOI 10.3390/life11010046,
Publication Year 2021
PubMed ID 33450886,
Patent ID NA,