SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06254

Signal sequence   GSIGAASMEFCFDVFKELKVHH

Length  22

Organism  Gallus gallus

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1JTI,

Predicted Structure ID  SPKB06254.cif

Structure  SPKB06254.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2452.82824

Aliphatic index  70.90909091

Isoelectric point  6.494922724

Charge (pH=7)   -0.878765573

Topological polar surface area  936.18

Aromaticity  0.136363636

Average rotatable bonds  3.681818182

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -6.9246

Hydropathy 



Literature Information


Title  Modulation of Cell Adhesion and Differentiation on Collagen Gels by the Addition of the Ovalbumin Secretory Signal Peptide

DOI  10.1021/acsbiomaterials.8b01505,

Publication Year  2019

PubMed ID  33405701,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.