SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06253

Signal sequence   MVGAIVLYVLLAAHSAFA

Length  18

Organism  Bombyx mori

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06253.cif

Structure  SPKB06253.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1846.26104

Aliphatic index  162.7777778

Isoelectric point  7.542349207

Charge (pH=7)   0.088042976

Topological polar surface area  627.16

Aromaticity  0.111111111

Average rotatable bonds  3.111111111

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  23

X logP energy  -1.5746

Hydropathy 



Literature Information


Title  18 Additional Amino Acids of the Signal Peptide of the Bombyx mori Nucleopolyhedrovirus GP64 Activates Immunoglobulin Binding Protein (BiP) Expression by RNA-seq Analysis

DOI  10.1007/s00284-020-02309-4,

Publication Year  2021

PubMed ID  33386938,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.