General Information
SPKB ID SPKB06251
Signal sequence MDWTWILFLVAAATRVHS
Length 18
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06251.cif
Physicochemical Information
Molecular weight 2117.49624
Aliphatic index 113.8888889
Isoelectric point 7.550936504
Charge (pH=7) 0.089336563
Topological polar surface area 778.17
Aromaticity 0.166666667
Average rotatable bonds 3.5
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 26
X logP energy -2.94863
Hydropathy 
Literature Information
Title Essentially Leading Antibody Production: An Investigation of Amino Acids, Myeloma, and Natural V-Region Signal Peptides in Producing Pertuzumab and Trastuzumab Variants
DOI 10.3389/fimmu.2020.604318,
Publication Year 2020
PubMed ID 33365032,
Patent ID NA,
